Platelet Function Assay (PFA) ADP/Collagen
|Profile or Test Panel||
Platelet Function Assay (PFA) Profile
Note: PFA values are only valid within certain platelet count and hematocrit ranges.
Complete Platelet Aggregation Profile
|Method||Aggregation measured in CT (closure time)|
|Test Information||The PFA is a screening test for platelet dysfunction. The cartridge membrane is coated with collagen, and with one of two platelet agonists (epinephrine or ADP). The platelets adhere to the collagen and aggregate in response to the collagen and epinephrine (or ADP). The response measured is known as the Closure Time (CT) and is reported in seconds. Depending on the results of this test, platelet aggregation testing may be necessary to establish the underlying cause.|
|Additional Test Information||Test is affected by high or low platelet counts and anemia. Samples with platelet counts >500,000/µl or <150,000/µl or samples with a hematocrit >50% or <35% may not give reliable results.
Results may be normal in the setting of specific platelet disorders, including platelet storage pool deficiency and in mild VWD. Normal ranges are included on testing report and can be made available upon request.
|Sample Requirements||Appointment required. It will be drawn at Bloodworks Northwest. Call Hemostasis Lab at 206-689-6594 to schedule an appointment.|
|Requisition Form||RFT- Hemostasis Reference Laboratory|
|Test Schedule||Monday – Friday|
|Turn around Time (analytic time)||Same day as scheduled visit|
|Report/Results||Fax number required to receive report|