Typical Rates, Volumes & Duration
Transfusion medicine
Typical Rates, Volumes, and Durations for Routine (Non-Emergent) Transfusions
|
Blood Component |
Adult |
Pediatric |
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|
Estimated Volume |
Duration |
Effect |
Dose, rate | Max dose and/or max rate | |
|
All, first 15 minutes |
100 mL/hr |
2 mL/kg/hr |
Do not exceed 100 mL/hr |
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|
Red Blood Cells |
350mL |
1 ½ -4 hrs |
One unit will increase hematocrit by approximately 3% or hemoglobin by 1gm/dL. |
2-5 ml/kg/hr |
Do not exceed 300 mL/hr |
|
Plasma |
200-250mL |
30-60 min. (max 4 hrs) |
One unit increases clotting factors approximately 2-5%. |
4-8 ml/kg/hr |
|
|
Platelets |
250-350mL |
1 hour |
One apheresis or a pool of 4 units will increase platelet count by approximately 30,000 – 60,000. |
4-8 ml/kg/hr |
|
|
Cryoprecipitate |
90-120mL |
15-30 min. |
One pool (5-6 units) increases fibrinogen count approximately 50mg/dL. |
4-8 ml/kg/hr |
|
|
Granulocytes |
220-450mL |
1-2 hrs. |
Dose: 10-20mL/kg Rate: 5-10 mL/kg/hr |
Max Dose: 20 mL/kg Max Rate: 10 mL/kg/hr |
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