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Medical Services

Transfusion medicine

 

Blood Component

 

Adult

 

Pediatric

Estimated Volume

Duration

Effect
(Non-bleeding 70 kg adult)

Dose, rate Max dose and/or max rate
 

All, first 15 minutes

   

100 mL/hr

   

2 mL/kg/hr

 

Do not exceed 100 mL/hr

 

Red Blood Cells

 

350mL

 

1 ½ -4 hrs

One unit will increase hematocrit by approximately 3% or hemoglobin by
1gm/dL.
 

2-5 ml/kg/hr

 

Do not exceed 300 mL/hr

 

Plasma

 

200-250mL

 

30-60 min. (max 4 hrs)

One unit increases clotting factors approximately 2-5%.  

4-8 ml/kg/hr

 
 

Platelets

 

250-350mL

 

1 hour

One apheresis or a pool of 4 units will increase platelet count by approximately 30,000 –
60,000.
 

4-8 ml/kg/hr

 
 

Cryoprecipitate

 

90-120mL

 

15-30 min.

One pool (5-6 units) increases fibrinogen count approximately
50mg/dL.
 

4-8 ml/kg/hr

 
 

Granulocytes

 

220-450mL

 

1-2 hrs.

   

Dose: 10-20mL/kg

Rate: 5-10 mL/kg/hr

 

Max Dose: 20 mL/kg Max Rate: 10 mL/kg/hr

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