Immunogenetics/HLA Laboratory Profiles

Testing for Individual HLA Alleles

Patients are tested for particular HLA alleles, for use in the diagnosis or treatment of various conditions. The following is a partial listing of HLA/disease or drug hypersensitivity associations.

Disease

Associated HLA Allele(s)

Birdshot Retinopathy Association

HLA-A*29

Ankylosing Spondylitis (and other arthropathies)

HLA-B*27

Behcet’s Disease Association

HLA-B*51

Celiac Association

HLA-DQB1*02
HLA-DQA1*05

Narcolepsy Association

DQB1 *0602

Drug Hypersensitivity

Associated HLA Allele(s)

Carbamazepine

B*1502

Abacavir

B*5701

HLA-B*5801 Typing

B*5801

     Note:   In addition to the above list we can type for any A, B, C, DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, DPB1, DPA1 alleles.

Testing Details for Individual HLA Alleles

  • Specimen Requirements:
    • One 10cc ACD blood (yellow top, solution A or B) tube
  • Labeling Requirements:
    • Specimen must have the patient’s first and last name, a date of draw and a unique identifier written on the tube.
  • Analytic Time:
    • See specific test for details.
  • Testing schedule:
    • Monday through Friday

All specimens must be accompanied by a Request for Testing Form

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