Apixaban Level

Also Known as (Alias) Eliquis
Indications Testing plasma level of Apixaban, an antithrombotic drug.
Method Chromogenic
Test Information Apixaban is detected with an  anti-Xa assay using an apixaban-specific standard
Additional Test Information A therapeutic range has not been determined.  Levels measured in patients on therapy vary widely.  If assessing steady-state levels, measurement at trough is recommended.
Sample Requirements Whole Blood:  3.2% Sodium Citrated (blue top)  OR
Frozen Plasma
Requested Volume Two 5 ml 3.2 sodium citrated (blue top) tubes as whole blood  OR
Frozen plasma in 4 X 1mL aliquots in plastic tubes
Sample Information Whole blood is preferred for testing but if it is not possible to send whole blood tubes TO ARRIVE HERE WITHIN 3 HOURS of collection then send frozen plasma. To prepare plasma centrifuge blue top tubes at 1500g for 15 minutes and remove the plasma and centrifuge a second time at 1500g for an additional 15 minutes.  Aliquot approximately 1 ml of plasma into 4 plastic tubes, and freeze.
Shipping Information Whole Blood:  Send at ambient temperature (18-25C) and must be received within the lab in less than or equal to 3 hours after collection.

Frozen Plasma:  send on dry ice

Send samples to:
Bloodworks Northwest
Attn: Hemostasis Laboratory
921 Terry Ave
Seattle, WA 98104

For additional information please see Ordering Information

Requisition Form RFT- Hemostasis Reference Laboratory

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