DNA Factor VIII Inversion
|Also Known as (Alias)
|Intron 1 or 22 Inversion
|Polymerase Chain Reaction (PCR) Based
|In severe hemophilia A, a common recurrent intron 22 gene inversion accounts for ~45% of the cases. A recurrent intron 1 inversion accounts for ~5% of the cases. These two sites are the first to be screened for severe hemophilia A patients.
|Additional Test Information
|If mutation is not identified, further screening can be performed by DNA Hemophilia A Mutation Evaluation testing information.
|EDTA (lavender top)
|3-10cc EDTA (lavender top) tube.
Analysis of amniocytes can be performed on cultured amniocytes. Two T-25 flasks of cells cultured to confluency will be accepted. Bloodworks Northwest does not have facilities to culture amniocytes.
|Whole blood shipped at ambient temperature and should arrive in the lab within 48 hours.
Send samples to:
Send cultured amniocyte samples to:
For additional information, please see Ordering Information-Bleeding Disorders
|Request for Testing Eastlake Bleeding Disorders Laboratory
|Turn around Time (analytic time)
|5 to 10 business days
|Fax number required to receive report