aPTT 1:1 Mix (incubated)
|Profile or Test Panel
Abnormal PT or aPTT Reflexive Evaluation Profile
Intrinsic Factor Evaluation Profile
Extrinsic Factor (abnormal PT) Evaluation Profile
Bleeding Diathesis with a Normal aPTT/PT Profile
Factor VIII Inhibitor Profile
Factor Inhibitor non-Factor VIII Profile
Fibrinolysis Evaluation Profile
Lupus Anticoagulant Profile
Abnormal result reflexes to the following tests as indicated.
von Willebrand Profile
|Also Known as (Alias)
|Patient with prolonged aPTT and suspected acquired factor inhibitor, particularly acquired FVIII inhibitor.
|Reflexive test if the aPTT 1:1 mix test is abnormal and etiology unknown.
|Additional Test Information
|If a specific inhibitor is suspected, then a 1:1 mix (patient plasma : normal plasma) is incubated at 37°C for 60 minutes. Then an aPTT is repeated. Normal ranges are included on testing report and can be made available upon request.
|Whole Blood: 3.2% sodium citrated (blue top) OR
|Two 5 ml 3.2% sodium citrated (blue top) tubes as whole blood OR frozen plasma in 4 X 1mL aliquots in plastic tubes.
|Minimum Volume or Pediatric Volume
|Frozen Plasma: at least 0.5ml in 2 plastic tubes.
|Whole blood is preferred for testing, but if it is not possible to send whole blood tubes TO ARRIVE HERE WITHIN 2 HOURS of collection, then send frozen plasma: Centrifuge blue top tubes at 1500g for 15 minutes and remove the plasma and centrifuge a second time at 1500g for an additional 15 minutes. Aliquot approximately 1 ml of plasma into 4 plastic tubes, and freeze.
|Whole Blood: Send at ambient temperature (18-25°C) and must be received within the lab in less than or equal to 2 hours after collection.
Frozen Plasma: Send on dry ice
Send samples to:
For additional information, please see Ordering Information
|RFT- Hemostasis Reference Laboratory
|Monday – Friday
|Turn around Time (analytic time)
|3 Business Day
|Fax number required to receive report